Publicación: Desarrollo de electrodos de grafeno inducido por laser (LIG) flexibles y estirables
| dc.contributor.advisor | Leal Ordoñez, José Andrés | |
| dc.contributor.author | Trujillo Minera, María del Pilar | |
| dc.contributor.director | Esquit Hernández, Carlos Alberto | |
| dc.date.accessioned | 2026-06-13T17:35:45Z | |
| dc.date.issued | 2025 | |
| dc.description.abstract | Los avances en la medicina moderna han revolucionado el tratamiento, diagnóstico y gestión de distintas enfermedades, mejorando la calidad de vida de las personas. Estas enfermedades, en muchos casos, pueden ser monitoreadas mediante electrodos, que funcionan como interfaz entre el tejido biológico y el circuito electrónico de medición o estimulación. Estos dispositivos permiten monitorear desde enfermedades cardiovasculares, donde se mide la actividad eléctrica del corazón, hasta lesiones musculares, donde juegan un papel fundamental en la recuperación. Actualmente, se han utilizado electrodos de grafeno inducidos por láser (LIG) por su simplicidad y bajo costo, sin embargo, es un material poco flexible, el cual limita sus aplicaciones en dispositivos que requieren adaptarse a los movimientos del cuerpo humano. Este proyecto tenía como objetivo desarrollar electrodos flexibles a base de grafeno inducido por láser (LIG) por medio de transferencia en seco a polímeros biocompatibles elásticos. En este caso se utilizó polidimetilsiloxano (PDMS), que es un material flexible y biocompatible que brindará mayor comodidad al paciente y mejor adaptación a la movilidad del cuerpo. Los electrodos fueron diseñados en Inventor y se fabricaron sobre sustratos de poliimida con una cortadora láser. Además, se caracterizaron electroquímicamente mediante técnicas como voltametría cíclica e impedancia electroquímica para evaluar sus propiedades antes y después de la transferencia. Asimismo, se realizaron mediciones de biopotenciales como electrocardiogramas (ECG) y electromiogramas (EMG) para evaluar su funcionamiento. Se obtuvieron electrodos flexibles capaces de medir señales eléctricas del cuerpo humano. | spa |
| dc.description.abstract | Advances in modern medicine have revolutionized the treatment, diagnosis, and management of various diseases, improving people’s quality of life. In many cases, these diseases can be monitored using electrodes, which act as an interface between biological tissue and the electronic measurement or stimulation circuit. These devices allow monitoring of everything from cardiovascular diseases, where the electrical activity of the heart is measured, to muscle injuries, where they play a fundamental role in recovery. Currently, laser-induced graphene (LIG) electrodes have been used because of their simplicity and low cost. However, this material is not very flexible, which limits its applications in devices that need to adapt to the movements of the human body. The aim of this project was to develop flexible electrodes based on laser-induced graphene (LIG) using dry transfer to elastic biocompatible polymers. In this case, polydimethylsiloxane (PDMS) was used, which is a flexible and biocompatible material that will provide greater comfort to the patient and better adaptation to body mobility. The electrodes were designed in Inventor and manufactured on polyimide substrates using a laser cutter. In addition, they were characterized electrochemically using techniques such as cyclic voltammetry and electrochemical impedance to evaluate their properties before and after transfer. Biopotential measurements such as electrocardiograms (ECG) and electromyograms (EMG) were also performed to evaluate their performance. Flexible electrodes capable of measuring electrical signals from the human body were obtained. | eng |
| dc.description.degreelevel | Pregrado | |
| dc.description.degreename | Licenciado en Ingeniería Biomédica | |
| dc.format.extent | 73 p. | |
| dc.format.mimetype | application/pdf | |
| dc.identifier.uri | https://repositorio.uvg.edu.gt/handle/123456789/6545 | |
| dc.language.iso | spa | |
| dc.publisher | Universidad del Valle de Guatemala | |
| dc.publisher.branch | Campus Central | |
| dc.publisher.faculty | Facultad de Ingeniería | |
| dc.publisher.place | Guatemala | |
| dc.publisher.program | Licenciatura en Ingeniería Biomédica | |
| dc.relation.references | G. Antonelli et al., «Laser-induced graphene wet transfer technique for lab-on-chip applications,» Sensors and Actuators A: Physical , vol. 377, pág. 115 746, oct. de 2024, issn : 0924-4247. doi : 10.1016/J.SNA.2024.115746 . | |
| dc.relation.references | S. Bai et al., «Laser-induced graphene: Carbon precursors, fabrication mechanisms, material characteristics, and applications in energy storage,» Chemical Engineering Journal , vol. 493, pág. 152 805, ago. de 2024, issn : 1385-8947. doi : 10.1016/J.CEJ. 2024.152805 . | |
| dc.relation.references | C. C. de Souza et al., «Flexible electrodes based on laser-induced graphene as an analy- tical platform to monitor amoxicillin,» Electrochimica Acta , vol. 508, pág. 145 221, dic. de 2024, issn : 0013-4686. doi : 10.1016/J.ELECTACTA.2024.145221 . | |
| dc.relation.references | E. P. Aparicio-Martínez, A. Vega-Rios, V. Osuna y R. B. Dominguez, «Salivary Gluco- se Detection with Laser Induced Graphene/AgNPs Non-Enzymatic Sensor,» Biosensors , vol. 13, pág. 207, 2 feb. de 2023, issn : 20796374. doi : 10.3390/BIOS13020207/S1 . dirección: https://www.mdpi.com/2079-6374/13/2/207/htm%20https://www.mdpi.com/2079-6374/13/2/207 . | |
| dc.relation.references | S. Aftab et al., «Laser-Induced Graphene for Advanced Sensing: Comprehensive Re- view of Applications,» ACS Sensors , sep. de 2024, issn : 23793694. doi : 10 . 1021 / ACSSENSORS . 4C01717 / ASSET / IMAGES / MEDIUM / SE4C01717 _ 0009 . GIF . dirección: https://pubs.acs.org/doi/abs/10.1021/acssensors.4c01717 . | |
| dc.relation.references | M. B. Kulkarni, N. H. Ayachit, T. M. Aminabhavi, A. K. Nayak y M. S. Hasnain, «Laser-induced graphene (LIG): Fabrication, challenges, and opportunities,» Materials and Components of Biosensors in Healthcare , págs. 467-482, ene. de 2025. doi : 10. 1016/B978-0-443-21676-3.00011-X . dirección: https://linkinghub.elsevier. com/retrieve/pii/B978044321676300011X . | |
| dc.relation.references | L. Wang, Z. Wang, A. N. Bakhtiyari y H. Zheng, «A Comparative Study of Laser- Induced Graphene by CO2 Infrared Laser and 355 nm Ultraviolet (UV) Laser,» Mi- cromachines , vol. 11, pág. 1094, 12 dic. de 2020, issn : 2072666X. doi : 10 . 3390 / MI11121094 . dirección: https://pmc.ncbi.nlm.nih.gov/articles/PMC7764730/ . | |
| dc.relation.references | A. Svetlova et al., «Benchtop Fabrication and Integration of Laser-Induced Graphene Strain Gauges and Stimulation Electrodes in Muscle on a Chip Devices,» Advanced Functional Materials , vol. 35, n. o 13, 2025. doi : 10.1002/adfm.202417184 . dirección: https://doi.org/10.1002/adfm.202417184 . | |
| dc.relation.references | R. Frisenda et al., «Recent progress in the assembly of nanodevices and vander Waals heterostructures by deterministic placement of 2D materials,» Chemical So- ciety Reviews , vol. 47, págs. 53-68, 1 ene. de 2018, issn : 14604744. doi : 10.1039/ C7CS00556C . dirección: https://www.researchgate.net/publication/320914362_ Recent _ progress _ in _ the _ assembly _ of _ nanodevices _ and _ van _ der _ Waals _ heterostructures_by_deterministic_placement_of_2D_materials . | |
| dc.relation.references | I. Miranda et al., «Properties and Applications of PDMS for Biomedical Engineering: A Review,» Journal of Functional Biomaterials , vol. 13, pág. 2, 1 mar. de 2021, issn : 20794983. doi : 10.3390/JFB13010002 . dirección: https://pmc.ncbi.nlm.nih.gov/ articles/PMC8788510/ . | |
| dc.rights.accessrights | info:eu-repo/semantics/openAccess | |
| dc.rights.coar | http://purl.org/coar/access_right/c_abf2 | |
| dc.rights.license | Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0) | |
| dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
| dc.subject.armarc | Grafeno | |
| dc.subject.armarc | Electrodos flexibles | |
| dc.subject.armarc | Nanomateriales | |
| dc.subject.armarc | Materials engineering | |
| dc.subject.armarc | Flexible electronics | |
| dc.subject.armarc | Laser-induced graphene | |
| dc.subject.ddc | 620 - Ingeniería y operaciones afines | |
| dc.subject.ods | ODS 3: Salud y bienestar. Garantizar una vida sana y promover el bienestar de todos a todas las edades | |
| dc.subject.ods | ODS 9: Industria, innovación e infraestructura. Construir infraestructuras resilientes, promover la industrialización inclusiva y sostenible y fomentar la innovación | |
| dc.title | Desarrollo de electrodos de grafeno inducido por laser (LIG) flexibles y estirables | spa |
| dc.type | Trabajo de grado - Pregrado | |
| dc.type.coar | http://purl.org/coar/resource_type/c_7a1f | |
| dc.type.coarversion | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |
| dc.type.content | Text | |
| dc.type.driver | info:eu-repo/semantics/bachelorThesis | |
| dc.type.version | info:eu-repo/semantics/publishedVersion | |
| dc.type.visibility | Public Thesis | |
| dspace.entity.type | Publication |
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